t(6;9)(p23;q34)
Pathology DEK-NUP214 (CAN-DEK) fusion gene The t(6;9)(p23;q34) associated DEK/CAN (CAN-DEK) fusion protein targets a population of long-term repopulating hematopoietic stem cells for leukemogenic...
View Article10q26.1-q26.3 loss
Pathology Loss of 10q26.1-q26.3 in association with 7q34-q36.3 gain or 17q24.3-q25.3 gain predict poor outcome in pediatric medulloblastoma. (#21652146#)References Loss of 10q26.1-q26.3 in association...
View Article7q34-q36.3 gain
Pathology Loss of 10q26.1-q26.3 in association with 7q34-q36.3 gain or 17q24.3-q25.3 gain predict poor outcome in pediatric medulloblastoma. (#21652146#)References Loss of 10q26.1-q26.3 in association...
View Article17q24.3-q25.3 gain
Pathology Loss of 10q26.1-q26.3 in association with 7q34-q36.3 gain or 17q24.3-q25.3 gain predict poor outcome in pediatric medulloblastoma. (#21652146#)References Loss of 10q26.1-q26.3 in association...
View ArticleHepatoblastoma oncogenetics
SummarySeveral genetic changes are shared with other embryonal tumors, such as loss of heterozygosity at chromosome 11p15, also described in rhabdomyosarcomas and Wilms tumors.Acquired mutations of the...
View Articlet(4;6)(q22;q15)
The t(4;6)(q22;q15) occurs in 11.7% of patients.The t(4;6)(q22;q15) is not independently associated with patient outcome. However, it occurs more frequently in high clinical T stage, high tumor volume...
View Article19q13.42 amplification
19q13 amplificationTumors embryonal tumor with abundant neuropil and true rosettes (ETANTR)References Embryonal tumor with abundant neuropil and true rosettes: a report of three cases of a rare tumor,...
View ArticleEGFR amplification
Pathology Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas. (#22472960#)References Paradoxical relationship between the degree of EGFR amplification and...
View Articlet(1;3)(p36;q21)
Pathology AML/MDS-associated t(1;3)(p36;q21) with Waldenström's macroglobulinemia (#7630185#)Reference Waldenström's macroglobulinemia with the AML/MDS-associated t(1;3)(p36;q21). Johansson B,...
View Articlet(9;14)(p13;q32)
Reference t(9;14)(p13;q32) involving the PAX-5 gene: a unique subtype of 14q32 translocation in B cell non-Hodgkin's lymphoma. Amakawa R, Ohno H, Fukuhara S. Int J Hematol. 1999 Feb;69(2):65-9. PMID:...
View Articlemolecular analysis of sarcomas
See also sarcomasReferences Impact of Molecular Analysis on the Final Sarcoma Diagnosis: A Study on 763 Cases Collected During a European Epidemiological Study. Neuville A, Ranchère-Vince D, Dei Tos...
View ArticleTFE3 rearrangement
References Utilization of a TFE3 Break-apart FISH Assay in a Renal Tumor Consultation Service. Green WM, Yonescu R, Morsberger L, Morris K, Netto GJ, Epstein JI, Illei PB, Allaf M, Ladanyi M, Griffin...
View Articletargeted seqencing in leukemias
Open references Next generation sequencing based multi-gene mutational screen foracute myeloid leukemia using miseq: applicability for diagnostics anddisease monitoring. Luthra R, Patel KP, Reddy NG,...
View Articlecancer gene sequencing panel
cancer gene sequencing panels; cancer gene NGS panelExamples in cancer gene predisposition renal cancer gene...
View Articlemutation screening in NSCLC
Reference Genetic Mutation Screen in Early Non-Small-Cell Lung Cancer (NSCLC) Specimens. Bar J, Damianovich M, Hout Siloni G, Dar E, Cohen Y, Perelman M, Ben Nun A, Simansky D, Yellin A, Urban D, Onn...
View Articlemutation screening in colorectal cancer
References DNA Testing and Molecular Screening for Colon Cancer. Carethers JM. Clin Gastroenterol Hepatol. 2013 Dec 17. pii: S1542-3565(13)01933-2. doi:10.1016/j.cgh.2013.12.007 . PMID: #24355100#
View ArticleEGFR mutation testing
EGFR testing; EGFR mutation testingReferences A Multicenter Blinded Study Evaluating EGFR and KRAS Mutation Testing Methods in the Clinical Non-Small Cell Lung Cancer Setting-IFCT/ERMETIC2 Project Part...
View Articlemutation testing in melanoma
mutation screening in melanoma; mutation detection in melanomaOpen references Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors. Anaka M,...
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